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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS1
All Species:
12.42
Human Site:
Y1158
Identified Species:
30.37
UniProt:
O60500
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60500
NP_004637.1
1241
134742
Y1158
P
T
Q
E
E
V
S
Y
S
R
G
F
T
G
E
Chimpanzee
Pan troglodytes
XP_524228
1241
134508
Y1158
P
T
Q
E
E
V
S
Y
S
R
G
F
T
G
E
Rhesus Macaque
Macaca mulatta
XP_001112314
1052
113512
F973
D
G
G
L
P
Q
R
F
Y
I
R
Y
E
A
L
Dog
Lupus familis
XP_541685
1242
135134
Y1158
P
T
L
E
E
M
S
Y
L
R
G
F
T
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS7
1242
134872
Y1158
P
T
L
E
E
V
S
Y
R
Q
A
F
T
G
I
Rat
Rattus norvegicus
Q9R044
1234
134286
V1151
L
P
P
T
L
E
E
V
L
Y
H
Q
G
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035777
1242
137333
Y1137
G
R
Q
E
N
P
H
Y
Y
Y
P
T
E
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08180
764
82987
R685
T
G
S
I
I
G
S
R
E
I
R
Q
D
N
G
Honey Bee
Apis mellifera
XP_624127
1307
143527
Y1217
D
P
G
S
G
S
Y
Y
P
S
M
S
P
T
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796903
1010
110769
W931
P
P
S
Y
A
P
S
W
D
S
Y
E
N
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80.9
87
N.A.
82.5
81.8
N.A.
N.A.
N.A.
N.A.
38.8
N.A.
20.9
26.9
N.A.
21.1
Protein Similarity:
100
99.5
83
92.6
N.A.
89.6
89.3
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
33.6
42.9
N.A.
35.9
P-Site Identity:
100
100
0
66.6
N.A.
66.6
6.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
13.3
73.3
N.A.
73.3
6.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
6.6
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
10
0
0
30
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
0
0
50
40
10
10
0
10
0
0
10
20
0
30
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
40
0
0
0
% F
% Gly:
10
20
20
0
10
10
0
0
0
0
30
0
10
30
20
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
20
0
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
20
10
10
0
0
0
20
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
50
30
10
0
10
20
0
0
10
0
10
0
10
10
10
% P
% Gln:
0
0
30
0
0
10
0
0
0
10
0
20
0
0
0
% Q
% Arg:
0
10
0
0
0
0
10
10
10
30
20
0
0
0
0
% R
% Ser:
0
0
20
10
0
10
60
0
20
20
0
10
0
0
0
% S
% Thr:
10
40
0
10
0
0
0
0
0
0
0
10
40
10
0
% T
% Val:
0
0
0
0
0
30
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
60
20
20
10
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _